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Dr. Sanaa Ahmed Khalifa
Document Details
Document Type
:
Article In Journal
Document Title
:
Studies on the effect of camel's milk and Urine on the duodenum of rats treated with antithrombosis drug Clexane (Enoxaparin Sodium)
دراسات على تاثير ألبان وأبوال الإبل على إثنى عشر الجرذان المعاملة بعقار مضاد التجلط (الكليكسان)
Document Language
:
English
Abstract
:
The present research was performed to study the effect of camels milk and urine on reduction of the toxicity of the antithrombosis drug (clexane) on the rats duodenum. Thirty adult male Rattus norvegieus rats were used for this study. Rats were divided into five groups containing 6 rats was subdivided into two subgroups (A) and (B). The first group was taken as control. The second group was daily subcutaneously injected with enoxaparin sodium equivalent to the human therapeutic dose 0.02 ml/rat for two weeks in subgroup (A) and for four weeks in subgroup (B), while the other three groups were daily subcutaneously injected with 0.02 ml of enoxaparin sodium and orally given 1.0 ml of the following therapies camels milk, camels urine and mixture of camels milk and urine for two weeks in subgroup (A) and for four weeks in subgroup (B). After this period the drug was stopped and the treatments were continues for two weeks in all subgroups (B) only. At the end of the experimental period the duodenum were processed for histological research. The main observed changes after two weeks of treatment of drug were increased goblet cells numbers, hemorrhage and lymphocytes infiltration in submucosa layer. This finding became more intensity after six weeks of treatment. In contrast the animals in groups 3 – 5 found the minimum abnormal histological changes in the duodenum structure, in addition to the mixture of camels milk and urine was more influence than milk or urine alone.
ISSN
:
16875559
Journal Name
:
Journal of the Egyptian Society of Biotechnolgy and Enviromental Sciences
Volume
:
9
Issue Number
:
1
Publishing Year
:
1427 AH
2007 AD
Article Type
:
Article
Added Date
:
Saturday, August 30, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سناء أحمد خليفة
Khalifa, Sanaa Ahmad
Researcher
Doctorate
mohammedkashif2000@yahoo.com
Files
File Name
Type
Description
34077.pdf
pdf
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